Dexinel cat tab (for worms)
Dexinel cat tab - broad-spectrum anthelmintic for cats. It is used for therapeutic and preventive purposes against nematode infections (toxocariasis, toxascaridosis, ancylostomiasis) and cestode infections (taeniasis, dipylidiasis, echinococcosis, mesocestoidiasis).
The drug has a wide spectrum of activity against roundworms and tapeworms parasitizing cats, including Toxocara cati (syn. mystax), Toxascaris leonina, Ancylostoma tubaeforme, Ancylostoma braziliense, Echinococcus multilocularis, Dipylidium caninum, Hydatigera (Taenia) taeniaeformis, Mesocestoides spp., and Joyeuxiella pasqualei.
Praziquantel, an active ingredient of the drug, works by depolarizing neuromuscular ganglia, disrupting glucose transport and microtubular function in cestodes, which leads to impaired muscle innervation, paralysis, and death of the parasite. Praziquantel is rapidly absorbed in the intestine, distributed in organs and tissues, and excreted mainly in metabolized form via urine.
Pyrantel embonate exhibits strong nematocidal activity by increasing cell membrane permeability, causing irreversible paralysis and muscle contraction in nematodes, leading to parasite death and elimination from the gastrointestinal tract. Pyrantel embonate is partially absorbed in the intestine, rapidly metabolized, and excreted mainly with feces.
each tablet contains active ingredients: pyrantel embonate – 230 mg and praziquantel – 20 mg, along with excipients: corn starch, microcrystalline cellulose (E460), polyvinylpyrrolidone K25, magnesium stearate (E572), colloidal anhydrous silica, hypromellose, polyethylene glycol 4000, titanium dioxide (E171).
The drug is prescribed to cats at a dose of 1 tablet per 4 kg of animal weight (5 mg praziquantel and 57.5 mg pyrantel embonate per 1 kg of animal weight).
| Cat weight, kg | Number of tablets |
| 1.0 - 2.0 | 1/2 |
| 2.1 - 4.0 | 1 |
| 4.1 - 6.0 | 1+1/2 |
| 6.1 - 8.0 | 2 |
contraindications for the use of the drug include individual hypersensitivity to any of its components (including a history of such reactions). kittens weighing less than 1 kg should not be dewormed.
the drug should not be used in pregnant females due to the lack of data on its effects in this group. it is also not recommended for kittens under three weeks of age, as cestode infestations are not detected in them.
adverse effects and complications are generally not observed when the drug is used according to the instructions. in cases of increased individual sensitivity to the active components, transient salivation, diarrhea, or vomiting may occur. these symptoms are short-lived, resolve on their own, and do not require medical treatment. no specific signs of overdose have been established. in cases of significant overdose, gastrointestinal disturbances and vomiting may occur. the use of dexinel with drugs containing piperazine is not recommended due to potential reduction in efficacy. the drug is not intended for use in productive animals.
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